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Manufacturing

ASI's Riverview facility to manufacture Ponatinib API By PBR Staff Writer
Contract Pharmaceutical Manufacturer Ash Stevens (ASI) has received approval from the US Food and Drug Administration (FDA) to allow its Riverview facility in Michigan to manufacture the Active Pharmaceutical Ingredient (API) in ARIAD Pharmaceuticals's oncology drug Iclusig (ponatinib).
Production & Manufacturing > Manufacturing > News
Catalent Pharma to expand Winchester controlled release manufacturing facility By PBR Staff Writer
Catalent Pharma Solutions, a global drug delivery technology and advanced supply solutions company, has revealed plans to expand its controlled release drug manufacturing facility in Winchester, Kentucky.
Production & Manufacturing > Manufacturing > News Sobi receives FDA clearance to manufacture Kineret in Austria By PBR Staff Writer
The US Food and Drug Administration (FDA) has granted approval for the manufacture of drug substance anakinra for Swedish Orphan Biovitrum AB’s (Sobi) Kineret at Boehringer Ingelheim's microbial site in Austria.
Production & Manufacturing > Manufacturing > News
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Bioprocess Development
12 June 2013
In development, we focus on all aspects of strain maintenance, cultivation, media optimization and bioprocess development at all levels as well as process management.
Production & Manufacturing > Manufacturing > Products
Fermentation Process Scale-up
12 June 2013
Our fermentation scientists have extensive experience and know-how on scaling-up the fermentation process to large-scale production.
Production & Manufacturing > Manufacturing > Products
Biosynthetic / Metabolic Engineering
12 June 2013
Whether to develop novel compounds by biosynthetic engineering (i.e. manipulation of biosynthetic enzymes and/or pathways), or to develop improved strains by manipulating key metabolic pathways, ACIES BIO uses state-of-the-art microbiology and molecular biology methods, including recombineering approaches, aided by systemic principles of genomics, transcriptomics and proteomics.
Production & Manufacturing > Manufacturing > Products
Biotransformation
12 June 2013
We provide development of recombinant microorganisms and/or expression of enzymes for biosynthesis or biotransformation of target compounds.
Production & Manufacturing > Manufacturing > Products
Heterologous Expression Systems
12 June 2013
We offer our clients the utilization of our highly efficient in-house developed heterologous expression systems based on Actinomyces and Bacillus high-producing strains to service your needs, including the heterologous expression of gene clusters encoding complex biosynthesis of secondary metabolites, as well as heterologous protein expression, optimized for production of biopharmaceuticals or industrially relevant enzymes.
Production & Manufacturing > Manufacturing > Products
Synthetic Chemistry
12 June 2013
ACIES BIO researchers have over four decades synthetic chemistry expertise in development of different synthetic and semi-synthetic products and scaling up developed synthetic routes to industrial production scale.
Production & Manufacturing > Manufacturing > Products
Downstream, Impurities Profiling and Analytics
12 June 2013
ACIES BIO can help you optimize your downstream process, develop analytical procedures or prepare custom-made standards for determination of different products or impurities.
Production & Manufacturing > Manufacturing > Products
Contract Manufacturing
12 June 2013
ACIES BIO offers custom microbial fermentation, biotransformation and synthetic chemistry services for small-scale production of natural, semi- or synthetic products.
Production & Manufacturing > Manufacturing > Products
Sobi receives FDA clearance to manufacture Kineret in Austria
12 June 2013 | By PBR Staff Writer
The US Food and Drug Administration (FDA) has granted approval for the manufacture of drug substance anakinra for Swedish Orphan Biovitrum AB’s (Sobi) Kineret at Boehringer Ingelheim's microbial site in Austria.
Production & Manufacturing > Manufacturing > News
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