Vetter Pharma International - High-Quality Aseptically Pre-Filled Injection Systems, Cartridges and Vials

Vetter is an independent international specialist in the production of aseptically pre-filled injection systems, cartridges and vials. For more than 25 years Vetter has been renowned for its quality, innovation and strategic partnerships. Vetter provides support for its pharmaceutical and biotech clients from the initial phases of development and regulatory approval process through to the successful product launch and market supply worldwide.

The fact that our products and processes have been approved by the FDA, the EMA and other authorities ensures the highest level of quality and safety. Our innovative patented application systems will help your product to attain a decisive edge in the market.

Vetter Development Service: Clinical development of products to market launch

Vetter Development Service specialises in supporting the clinical development of products to market launch. Tailoring of the application system to the active substance can accelerate time-to-market and maximises market impact. As experts in the handling of highly sensitive active substances, you can rely upon our experience in quick, efficient and careful production processes with freeze-dried active substances.

Prior to clinical production, pharmaceutical analyses are conducted to assess production feasibility. We then support the selection of the most suitable injection system to its specifications. Once the clinical stage is complete, we focus on finding methods for a gentle, swift and economic production of your product. At the same time we support your efforts to obtain international regulatory approvals.

Consulting the Vetter experts at the earliest possible stage of drug development saves time and money and will help your product attain a decisive edge in the market.

Vetter Development Service includes:

• Primary packaging development
• Process development
• Clinical manufacturing
• Pharmaceutical analysis
• Regulatory affairs services
• Transfer to Vetter commercial manufacturing

Vetter Commercial Manufacturing: Sterile filling to custom-packing of the final product

Our focus is on aseptically pre-filled injection systems. We utilise and are experienced in a large array of standard syringe systems, cartridges, vials and our own patented application systems.

Vetter Commercial Manufacturing handles all aspects of drug production from sterile filling to custom-packing of the final product. We successfully apply a full range of cutting-edge technology in the sterile production of your product, such as Restricted Access Barrier Systems (RABS). Liquid parenteral drugs and lyophilised drugs are manufactured in our state-of-the-art manufacturing sites.

You can also rely upon our experience in the production (form, fill and finish) of modern biopharmaceutical drugs and our support through the regulatory approval process. Our quality assurance system monitors the products and processes to ensure conformity with the agreed quality specifications and regulatory requirements.

Vetter Commercial Manufacturing includes:

• Fill and finish
• Packaging service
• Pharmaceutical analysis
• Regulatory affairs services

Ahead of your competitors by the length of a syringe: Vetter Solutions

As a result of our high quality, efficient production processes and patient-friendly designs, Vetter pre-filled systems excel in the marketplace. This is particularly true of our own patented innovations. Here are just a few examples.

The Vetter Lyo-Ject® dual-chamber ready-to-use syringe for example is designed for sensitive drugs, which will not degrade in a lyophilised state. The actual active ingredient is lyophilised in one chamber, while the other chamber of the syringe contains a solvent that is mixed with the active substance immediately before application. This all-in-one concept provides for a long shelflife as well as easy handling. This also means higher yields of your active product ingredient and precision in dosing.

Our innovative systems not only appeal to patients, but will also help your product to attain a decisive edge in the marketplace. This creates genuine value added for our partners and our customers.

Vetter Solutions include:

• Dual-chamber technology, e. g. suitable for lyophilized, liquid and powdered substances:
  - lyophilisate/solvent
  - liquid/liquid
  - powder/liquid
• Anti-counterfeiting solutions
• Dosage forms: Syringes, cartridges, vials

Vetter Pharma International GmbH
Eywiesenstraße 5
88212 Ravensburg, Germany

Tel: +49-751-3700-0
Fax: +49-751-3700-4000
info@vetter-pharma.com
www.vetter-pharma.com