Log in or Register for enhanced features | Forgotten Password?
White Papers | Suppliers | Events | Report Store | Companies | Dining Club | Medical Devices | Videos
Production & Manufacturing
Manufacturing
Return to: PBR Home | Production & Manufacturing | Manufacturing | White Papers
Search Refinements

Manufacturing White Papers

View white papers from other Pharmaceutical sectors:
136-150 of 167 results
Quality By Design: The Automated Pharmaceutical Assay
| By Sotax
Who can argue against the concept of Quality by Design (QbD) in the pharmaceutical industry? We should always strive to improve our systems and the way tasks are accomplished. The pharmaceutical industry should be no exception. One lofty definition of QbD according to the FDA is “A maximally efficient, agile, flexible pharmaceutical manufacturing sector that reliably produces high quality drug products without extensive regulatory oversight.” Coming back down to earth for a moment it is logical to assume that Chemistry, Manufacturing, and Controls (CMC) should be at the core of this initiative. In the pharmaceutical laboratory, QbD challenges our understanding of the product. It requires more robust and rugged methods that can provide more information and be efficiently executed.
Production & Manufacturing > Manufacturing > White Papers
Benefits of Automated Sample Preparation in Pharmaceutical Development and Quality Operations
| By Sotax
When we think of automation many images come to mind such as large robots bolting on doors on cars in seconds or the mesmerizing packaging machinery most pharmaceutical companies employ. In the pharmaceutical laboratory there are various types of automated instruments. Some automated devices have become ubiquitous. The auto injector on an HPLC is a tool that most consider indispensable. Fully automated sample preparation and dissolution analysis are common however their perceived benefits for purchase justification are primarily confined to labor savings. This article will explore additional ways that laboratory automation can pay off in a big way.
Production & Manufacturing > Manufacturing > White Papers
Automated Sample Preparation for Creams, Gels and Difficult Samples
| By Sotax
Sample preparation for creams, lotions, gels and ointments is a difficult task. Their high viscosity or unique rheology causes analyte extraction of these sample types to be particularly difficult to disperse. They are most troublesome when the semi-solid base product is not miscible with the preferred solvent required for the assay. This poster will illustrate how automated sample preparation can be utilized to overcome these difficulties. One benefit of automated sample preparation is its ability to eliminate differences in various manual techniques such as sample dispersion.
Production & Manufacturing > Manufacturing > White Papers
Automated Cleaning Swab Validation Testing Using the Zymark® APW3 Assay Workstation
| By Sotax
Analysis of cleaning swabs provides its own set of challenges to the pharmaceutical laboratory. The large numbers of samples and sporadic requests to the lab make it an ideal candidate for automation. Automated serial processing of swab samples can improve both the analytical quality and laboratory responsiveness.
Production & Manufacturing > Manufacturing > White Papers
Pharma News Special
| By Shimadzu PBR
For the latest pharmaceutical industry news from Shimadzu, please download the free White Paper below.
Production & Manufacturing > Manufacturing > White Papers
Dual Ion Source DUIS-2020 for Simultaneous ESI and APCI Measurement
| By Shimadzu PBR
In LCMS measurement, the ionization mode is selected depending on the polarity of the target compounds. For example, Electrospray Ionization (ESI) is generally selected for analysis of high-polarity compounds which are typically found in drugs and pesticides, while Atmospheric Pressure Chemical Ionization (APCI) is selected for compounds having lower polarity.
Production & Manufacturing > Manufacturing > White Papers
Reduced Solvent Consumption and Operational Costs with Existing LC Systems
| By Shimadzu PBR
Switching to the Prominence UFLC ultra-high-speed LC as a means of reducing solvent consumption and operational costs was introduced in Technical Report No. 24 "Reduced Solvent Consumption and Operational Costs with Ultra High Speed Analysis." Although introduction of ultra-highspeed LC is an effective way to conserve solvent, there is a very significant issue as to how this can be achieved with the existing LC systems in use. This report introduces detailed suggestions on how to most effectively reduce solvent consumption with existing LC systems.
Production & Manufacturing > Manufacturing > White Papers
Reduced Solvent Consumption and Operational Costs with Ultra High Speed Analysis
| By Shimadzu PBR
HPLC-grade acetonitrile and methanol are used in many applications due to their chemical stability and low impurity content. Acetonitrile is generally used as a mobile phase more than methanol because (1) it subjects the column to less pressure to permit a longer column life, and (2) there are fewer obstructions in the short wavelength region in UV detection.
Production & Manufacturing > Manufacturing > White Papers
Reducing Analysis Limitations by Using Multiple Detectors with Ultra-Fast LC
| By Shimadzu PBR
In HPLC method development, it is important not only to focus on the substance of interest, but also to pay attention to impurities. In both process and quality control, care must be taken with respect to unanticipated impurities in the sample to maintain a high level of product quality. When using ultra fast LC in particular, appropriate measures must be taken to ensure that impurities are not overlooked during the shortened analysis time achieved with higher speeds.
Production & Manufacturing > Manufacturing > White Papers
Improved R&D Efficiency in Compound Synthesis, Confirmation and Purification
| By Shimadzu PBR
Research departments in various fields, especially those in the pharmaceutical manufacturing and chemical-industries, are involved in the synthesis of compounds and the subsequent confirmation and purification of those compounds. Often, the greatest major concern of researchers handling great numbers of samples is how to achieve data as quickly and easily as possible.
Production & Manufacturing > Manufacturing > White Papers
Accurate Mass Measurement of High Concentration Samples by LCMS-IT-TOF
| By Shimadzu PBR
Time of flight (TOF) type mass spectrometers are used because they are capable of providing accurate high-resolution mass information. Mass accuracy for TOF analysers can deteriorate under certain conditions when analysing high concentration samples
Production & Manufacturing > Manufacturing > White Papers
Annual Report 09: Intelligent Materials
| By Heraeus
In 2009, we generated more than €2.6 billion in product revenue and €13.6 billion in precious metals trading revenue with more than 12,300 employees in over 110 subsidiaries.
Production & Manufacturing > Manufacturing > White Papers
Biovian - From Gene to Finished Vial
| By Biovian
Comprehensive information about Biovian, including detailed information on all services as well as examples.
Production & Manufacturing > Manufacturing > White Papers
Biovian Company Brochure
| By Biovian
From gene to finished vial — Biovian is your one-stop-shop providing full range services in cGMP contract manufacturing of biologicals.
Production & Manufacturing > Manufacturing > White Papers
Chinese Regulatory Changes for Human Serum and Plasma Exports Trigger Potential Delays
| By World Courier
Researchers conducting or planning to conduct clinical trials in China should be aware of new regulatory changes that specifically affect export shipments of human serum and plasma from China and the delays that the new administrative process may create. This free white paper includes a list of these major changes associated with the new regulations.
Production & Manufacturing > Manufacturing > White Papers
136-150 of 167 results